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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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Cautions

Sexual Contiguria:

If you have had an erection for a long time, it is encouraged to consult your doctor before taking Cialis or similar medications. This may be because you have an underlying medical condition, or you are taking other medicines. Do not exceed the recommended dose. Let your doctor know if the condition develops.

Do not use Cialis or similar medications if you:

  • Are allergic to tadalafil or any ingredients in any medications that treat any allergic reaction.
  • Have a condition that may be reversible or 6-monthly maintenance therapy with Cialis or similar medications.
  • Take any nitrate medication with this product as directed.
  • Take riociguat with Cialis as instructed by your doctor.
  • Have a history of fainting, lightheadedness, angina, heart attack, or stroke.

Comparing Cialis vs Viagra

What are Cialis vs Viagra?

Cialis and Viagra are two of the most popular erectile dysfunction medications available in the U. S., although they are both prescription medications. While Viagra (sildenafil) and Cialis (tadalafil) are both PDE5 inhibitors, they differ in how they are taken. Cialis typically takes about 30 minutes to work, while Viagra’s effects last up to 36 hours. While Viagra’s effects last longer, Cialis has a longer onset of action. Cialis lasts up to 4-5 hours, and Viagra’s effects last up to 36 hours.

Both medications have similar side effects, so it’s always a good idea to speak with a healthcare provider before taking either one.

What’s the Difference Between Cialis and Viagra?

When it comes to Cialis vs Viagra, they are both PDE5 inhibitors. Both are PDE5 inhibitors that help to relax the muscles in the penis, allowing for firmer, more erections. Cialis has a longer duration of action, with effects lasting up to 36 hours. On the other hand, Viagra takes slightly longer to kick in, with effects lasting up to 36 hours.

So, when it comes to Cialis vs Viagra, it’s important to talk with a healthcare provider first. They can help you understand how each medication works and provide accurate information for your specific health needs. They can also recommend other medications you can take to avoid any potential side effects.

Can I Take Cialis and Viagra Together?

Cialis and Viagra should never be taken together. Both medications are PDE5 inhibitors that help to relax the muscles in the penis, allowing for firmer, more erections. Both Cialis and Viagra are designed to be taken as prescribed by a healthcare professional.

How Do They Work?

Cialis and Viagra both work by inhibiting the PDE5 enzyme, which is responsible for the production of the PDE5 (phosphodiesterase 5). This allows more blood to flow into the penis, facilitating stronger and longer-lasting erections. Both medications work by inhibiting the production of the PDE5 enzyme, which results in a stronger and longer-lasting erection. They both also have similar side effects, so it’s always a good idea to speak with a healthcare provider before taking either one.

Are They Similar?

While both medications are PDE5 inhibitors, Cialis and Viagra have different uses, and their effectiveness may vary depending on the specific medication they are being used for. It’s important to discuss all medications, supplements, and other medications you’re taking with your healthcare provider before starting any new medication.

Sildenafil

Sildenafil Citrate

Active: Sildenafil

Inactive: Sildenafil

Packing: 4 tablets per pack

Sildenafil Citrate is a phosphodiesterase type 5 (PDE5) inhibitor used for the treatment of erectile dysfunction (ED) and pulmonary arterial hypertension (PAH) in men. The active ingredient is Sildenafil Citrate, a PDE5 inhibitor.

Sildenafil citrate, known for its high potency and rapid onset of action, belongs to a group of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. This class of drugs is used for the treatment of erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). It works by inhibiting the action of PDE5, thus preventing the degradation of penile tissues.

Sildenafil citrate is also used as an adjunct therapy to other erectile dysfunction medications, such as Viagra, Cialis, and Levitra. It is also used for the treatment of pulmonary arterial hypertension (PAH), a condition in which the arteries in the lungs become enlarged and the blood pressure in the lungs decreases. However, it is not recommended to take Sildenafil citrate with any other class of medications due to its potential to interact with other medications, such as tadalafil and sildenafil.

The PDE5 inhibitors in this class of drugs include sildenafil citrate, tadalafil, vardenafil and vardenafil. It is important to note that there may be some interactions between the two drugs.

The recommended dose of Sildenafil Citrate for ED treatment is 100mg, taken orally. The recommended dosage of sildenafil citrate is 1,000mg, taken orally. The dose may be increased to 2,000mg, taken orally, depending on the patient's response and tolerability. The recommended dose for PAH treatment is 5mg, taken orally, for 4-6 hours. The maximum recommended dosing frequency is once per day.

Erectile Dysfunction

Erection problems (impotence) are very common, particularly in men over 40.

Most men occasionally fail to get or keep an erection. This is usually due to stress, tiredness, anxiety or drinking too much alcohol, and it’s nothing to worry about.

If it happens more often, it may be caused by physical or emotional problems.

Physical causes Possible cause Treatment Narrowing of penis blood vessels, high blood pressure, high cholesterol medicine to lower blood pressure, statins to lower cholesterol Hormone problems hormone replacement – for example, testosterone Side effects of prescribed medication change to medicine following discussion with GP You may also be asked to make lifestyle changes.

Do lose weight if you’re overweight stop smoking eat a healthy diet exercise daily try to reduce stress and anxiety

Don’t cycle for a while (if you cycle more than 3 hours a week) drink more than 14 units of alcohol a week

  • Side Effects

    Possible side effects

    Like all medicines, this medicine can cause side effects, although not everybody gets them. These effects are normally mild to moderate in nature.

    If you experience any of the following side effects stop using the medicine and seek medical help immediately:

    allergic reactions including rashes (frequency uncommon). chest pain – do not use nitrates but seek immediate medical assistance (frequency uncommon). priapism, a prolonged and possibly painful erection after taking CIALIS (frequency rare). If you have such an erection, which lasts continuously for more than 4 hours you should contact a doctor immediately. sudden loss of vision (frequency rare). Other side effects have been reported:

    Common (seen in 1 to 10 in every 100 patients)

    headache, back pain, muscle aches, pain in arms and legs, facial flushing, nasal congestion, and indigestion. Uncommon (seen in 1 to 10 in every 1,000 patients)

    dizziness, stomach ache, feeling sick, being sick (vomiting), reflux, blurred vision, eye pain, difficulty in breathing, presence of blood in urine, prolonged erection, pounding heartbeat sensation, a fast heart rate, high blood pressure, low blood pressure, nose bleeds, ringing in the ears, swelling of the hands, feet or ankles and feeling tired. Rare (seen in 1 to 10 in every 10,000 patients)

    fainting, seizures and passing memory loss, swelling of the eyelids, red eyes, sudden decrease or loss of hearing, hives (itchy red welts on the surface of the skin), penile bleeding, presence of blood in semen and increased sweating. Heart attack and stroke have also been reported rarely in men taking CIALIS. Most of these men had known heart problems before taking this medicine.

    Partial, temporary, or permanent decrease or loss of vision in one or both eyes has been rarely reported.

  • abinit 20% beryllium gonoride inhibitors oral diabetes treatment with beryllium supplements daily capsule4 weekly daily daily daily tablet 2.5mg and 5mg tadalafil 20mg 5mg daily daily daily daily daily injection Tadalafil is a medication originally used to treat erectile dysfunction. It was later used as a treatment for benign prostatic hyperplasia (BPH) and male pattern hair loss. CIALIS was later used to treat male pattern hair loss. However, as with all medications, the side effects associated with CIALIS may cause side effects not witnessed by doctor.

    When you are taking CIALIS you may experience some other side effects, including:

    headache, back pain, muscle ache, pain in your arms and legs, feelings of anxiety, weight gain, swelling of your hands, feet, and ankles, red eyes, sudden decrease or loss of hearing, growth of blackheads and black legs.

    Common (seen in 1 to 20 in every 40, 60 or up to 80% of patients)

    headache, back pain, muscle ache, feeling sick (nausea), chest pain, reflux, indigestion, indigestion-like symptoms, see a doctor in a shrouded in the the airiness of a head cold medicine such as CIALIS may prohibit an erection for more than 4 hours. If you have such symptoms you should seek medical help immediately.

    Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

    Common side effects reported from Cialis use include:

    • Headache
    • Indigestion
    • Heartburn
    • Upset stomach
    • Gas
    • Nausea
    • Flushing

    More severe side effects include:

    • Painful erections or erections that last longer than 4 hours
    • Sudden loss of vision
    • Sudden loss of hearing
    • Ringing in the ears
    • Chest pain
    • Shortness of breath
    • Painful urination
    • Increased urination frequency
    • Fainting
    • Dizziness
    • Skin rash
    • Hives
    • Facial swelling

    If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

    As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

    Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

    In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

    Read more about Cialis.

    is a prescription drug. All rights belong to the manufacturer. If you are experiencing a symptom-Brucella Sincoma viral infection, please get in the know your treatment.